COMPARISON OF GENE EXPRESSION AND BIOTRANSFORMATION ACTIVITY OF HEPARG CELLS UNDER STATIC AND DYNAMIC CULTURE CONDITIONS

Comparison of gene expression and biotransformation activity of HepaRG cells under static and dynamic culture conditions

Abstract Flow conditions have been shown to be important in improving longevity and functionality of primary hepatocytes, but the impact 518 of flow on HepaRG cells is largely unknown.We studied the expression of genes encoding CYP enzymes and transporter proteins and CYP1 and CYP3A4 activity during 8 weeks of culture in HepaRG cells cultured under

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A Re-Evaluation of the Chasmosaurine Ceratopsid Genus Chasmosaurus (Dinosauria: Ornithischia) from the Upper Cretaceous (Campanian) Dinosaur Park Formation of Western Canada.

BACKGROUND:The chasmosaurine ceratopsid Chasmosaurus is known from GLUCOLIZER the Upper Cretaceous (Campanian) Dinosaur Park Formation of southern Alberta and Saskatchewan.Two valid species, Chasmosaurus belli and C.russelli, have been diagnosed by differences in cranial ornamentation.Their validity has been supported, in part, by the reported stra

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Quantifying the Impact of Atmospheric Deposition on the Biogeochemistry of Fe and Al in the Upper Ocean: A Decade of Collaboration with the US CLIVAR-CO2 Repeat Hydrography Program

The aerosol deposition of continental material and its partial dissolution in the surface ocean exerts an important control on the distribution of iron and other potentially limiting trace metal (TM) micronutrients in the open ocean.This dust deposition has implications for the regulation of global climate through the coupling of biolimiting TM cyc

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